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Chibani-Chennoufi S, Sidoti J, Bruttin A, Kutter E, Sarker S, Brussow H

The prevalence and severity of periodontal disease in mainland China: Data from the fourth national oral health survey (2015-2016)

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7.2 Current management approaches: to optimize drug delivery systems Despite the promising pharmacologic effects of artemisinin and its derivatives, their clinical applications are limited due to their poor aqueous solubility, short half-life in blood circulation, low bioavailability, and poor stability (Qian et al., 2021)